1 Blood Oxygen Binding in Hypoxaemic Calves
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Blood oxygen transport and tissue oxygenation have been studied in 28 calves from the Belgian White and Blue breed (20 healthy and eight hypoxaemic ones). Hypoxaemic calves have been chosen according to their excessive respiratory frequency and to their low partial oxygen strain (PaO2) in the arterial blood. Venous and BloodVitals SPO2 arterial blood samples had been collected, and 2,3-diphosphoglycerate, adenosine triphosphate, BloodVitals home monitor chloride, inorganic phosphate and hemoglobin concentrations, and pH, PCO, and PO2 have been determined. An oxygen equilibrium curve (OEC) was measured in customary circumstances, for each animal. The arterial and venous OEC have been calculated, taking body temperature, pH and PCO2 values in arterial and venous blood into account. The oxygen trade fraction (OEF%), corresponding to the diploma of blood desaturation between the arterial and BloodVitals home monitor the venous compartments, and the amount of oxygen launched on the tissue degree by a hundred mL of blood (OEF Vol%) have been calculated from the arterial and venous OEC combined with the PO2 and hemoglobin focus. In hypoxaemic calves investigated on this study, the hemoglobin oxygen affinity, measured beneath commonplace conditions, BloodVitals insights was not modified. On the contrary, in vivo acidosis and hypercapnia induced a decrease in the hemoglobin oxygen affinity in arterial blood, which combined to the decrease in PaO2 led to a lowered hemoglobin saturation degree in the arterial compartment. However, this didn't impair the oxygen change fraction (OEF%), because the hemoglobin saturation degree in venous blood was also diminished.


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